Newly diagnosed with Multiply Myeloma, information on your planned Essay

Newly diagnosed with Multiply Myeloma, information on your planned treatment with Lenalidomide 2 - Essay Example There is also elevated levels of antibodies and also other plasma proteins. In vitro, effects of lenalidomide 2 include direct anti-tumor action. It inhibits the microenvironment support for the thriving of the tumor cells. It plays an immunomudulary role. In vivo, it leads to the apoptosis of tumor cells both directly and indirectly. It does this by inhibition of support for bone marrow stromal cells. It also has anti-osteocaltrogenic, anti-angiogenic, and immunomodulary activities. The choice of chemotherapy would depend on factors such as the health of the patients, future ability to undergo stem cell transplantation, age and also disease characteristics that indicate a high risk to MM. Treatment options for patients with high risk of multiple myeloma is indistinct. It is recommended that patients of that nature enrol in clinical trials. Patients who are unwilling to participate in clinical trials would have a regimen that should include a combination that has bortezomib. After initial chemotherapy, stem cell transplanataton is recommended. For standard risk MM, the treatment options include a drug without melphalan, such as lenalidomide 2 and dexamethasone (RD), or cyclophosphamide , dexamethasone and bortezomib (VCD). In case the patient would not undergo stem cell transplantation, treatment should include thalidomide, melphalan and prednisone (MPT) or prednisone, bortezomib and melphalan (VMP). Another suitable combination is lenalidomide 2, with dexamethasone in low doses (RD). Lenalidomide 2, an immunomudalting agent, is usually effective in the treatment of MM. It is most often used in combination with dexamethasone. The combination is taken in the form of pills for between 3 to 4 weeks, dexamethasone being taken weekly. Due to the tendency to lead to formation of clots, warfarin or aspirin is given to reduce the risk. Kumar, S., Flinn, I.W., Hari, P.N. et al (2009). Novel three- and four-drug combinations of bortezomib, dexamethasone,

Reflective Report Essay Example | Topics and Well Written Essays - 1000 words

Reflective Report - Essay Example The presentation was prepared by our group consisting of 5 people. The presentation consists of total 15 slides for which the information and data was collected and organized by all of the group members. In order to organize the work, we divided the work equally among all the members. The selection of the centre was done after visiting the centre and a detailed discussion between the group members. After deciding the centre we discussed the length and parts of the presentation and it was decided that the presentation would be around 14-16 slides and the main parts would be introduction, body, finance structure of the centre and their consultation and other services. The group members are assigned different parts of the presentation and I decided to complete the introduction part. In order to collect the information for the assigned parts, we visited the centre several time and spent time with the staff, at their library and around the centre. The staffs of the centre was very coopera tive and willing to share information with us due to which there was no major problem faced in gathering data and information. After collecting the information and data all of the group members finalize their part and then we sit together to connect all of these parts and make the final presentation. This task was also done finely and eventually we came up with the complete presentation within the given time. This preparation of the presentation was a great opportunity for me to learn about the dynamics of group work. I learnt a lot about the problems and services of the centre selected for the presentation but more worthwhile are the experiences and lessons that I learnt during the time span of making this presentation. The group also encountered some little communication and coordination problems but fortunately none of these problems lasts for long enough to affect our final work. The members of our group were from different backgrounds and problems. Two of us were part time work ers at a local enterprise and due to their bust schedule the group frequently faces problems in deciding the meeting time and place. Most of the time, we decided to meet on the weekends and the place was decided keeping in view the convenience of all the members. We also have little differences while deciding the layout of the presentation because all of the group members had different ideas in their minds and it was really difficult to incorporate the ideas and wishes of all the four students in a single presentation. We tried to cope up with this problem by compromising at several stages and giving respect to the ideas and desires of each other but it was certainly not an easy task. Our first visit to the centre was an exciting experience for us. We had already decided what sort of information is required for each of the part and this everyone was looking for the information to complete the section assigned to him. While I was looking for history and general structure of the centr e, my fellows were seeking for their financial data. I faced no problem in acquiring information about the centre due to the cooperation of the staff but a little problem was raised when the staff of the centre informed that they will not financial information and data because they keep it confidential from the general public. At first, we were disappointed because